Poka-yoke (ポカヨケ^?) (IPA: [poka joke]) is a Japanese term that means “fail-safing” or “mistake-proofing”. A poka-yoke is any mechanism in a Lean manufacturing process that helps an equipment operator avoid (yokeru) mistakes (poka). Its purpose is to eliminate product defects by preventing, correcting, or drawing attention to human errors as they occur. The concept was formalised, and the term adopted, by Shigeo Shingo as part of the Toyota Production System. [Wikipedia]

Peter Abilla offers a great new example of design that accommodates human frailty: Embeda, a newly FDA-approved pain-killer with

…an interesting property: If you take the medication as prescribed, it works fine; if you abuse the medication, it ceases to work.

…EMBEDA(TM) contains extended-release morphine pellets, each with an inner core of naltrexone hydrochloride, an opioid receptor antagonist. If taken as directed, the morphine relieves pain while the sequestered naltrexone hydrochloride passes through the body with no intended clinical effect. If EMBEDA(TM) is crushed or chewed, the naltrexone is released and absorbed with the morphine, reversing the morphine’s subjective and analgesic effects.

After all, if pain killers can’t relate to human weakness, what can?